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The lab's research interests focus on understanding how proteases and anti-proteases may regulate tumour development, particularly immune cell (T-cells and macrophages) and endothelial cell function in lung cancers. Specifically, the lab aims to assess how proteases and anti-proteases can alter cell phenotypes and behaviours, and to unravel the multifaceted immune mechanisms that allows these pulmonary enzymes to manipulate the tumour microenvironment leading to tumour progression, metastasis and poor response to anti-cancer therapies